NAMs.network is the first open, continuously updated database of New Approach Methodologies meeting EU and US regulatory requirements in the safety assessment of chemicals and nanomaterials. The platform combines in vitro, in chemico and in silico data, classifies NAMs by status (validated, in validation, promising) and enables multi-criteria filtering (endpoint, biological system, regulatory). With an intuitive interface, it accelerates the selection of non-animal alternatives, supports SSbD and the Green Deal, reduces costs, testing time and CO₂ emissions, and gives NAMs suppliers free global exposure.